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Protective effect of Nigella sativa oil against thioacetamide-induced liver injury in rats
- Source :
- Medicine Science, Vol 6, Iss 1, Pp 96-103 (2017)
- Publication Year :
- 2017
- Publisher :
- Society of TURAZ AKADEMI, 2017.
-
Abstract
- antioxidant which is known to have liver protective effects, against thioacetamide (TAA)-induced liver injury. Accordingly, we aimed to investigate the toxicity of a hepatotoxic agent, thioacetamide, compared the NSO and NAC liver preventive effects in experimental animal model. Wistar-albino rats were randomly allocated to five groups, each consisting of eight rats, and were subjected to different treatment regimens for 6 days. Alanine aminotransferase (ALT), malondialdehyde (MDA), and protein carbonyl (PC) levels decreased significantly by NSO treatment (P [Med-Science 2017; 6(1.000): 96-103]
- Subjects :
- Liver injury
lcsh:R5-920
Antioxidant
business.industry
medicine.medical_treatment
lcsh:R
Thioacetamide (TAA)
lcsh:Medicine
Nigella sativa oil (NSO)
ROS
Pharmacology
medicine.disease
Malondialdehyde
chemistry.chemical_compound
N-acetylcysteine (NAC)
chemistry
Liver
Toxicity
Nigella sativa oil
medicine
Alanine aminotransferase
Thioacetamide
Protein carbonyl
business
lcsh:Medicine (General)
Subjects
Details
- Language :
- English
- ISSN :
- 21470634
- Volume :
- 6
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Medicine Science
- Accession number :
- edsair.doi.dedup.....03eac780f6b973ac12712f5c21061acb