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Protective effect of Nigella sativa oil against thioacetamide-induced liver injury in rats

Authors :
Sedat Bilgic
Elif Ozerol
Cemil Colak
Kevser Tanbek
Nurhan Sahin
Mustafa Iraz
Source :
Medicine Science, Vol 6, Iss 1, Pp 96-103 (2017)
Publication Year :
2017
Publisher :
Society of TURAZ AKADEMI, 2017.

Abstract

antioxidant which is known to have liver protective effects, against thioacetamide (TAA)-induced liver injury. Accordingly, we aimed to investigate the toxicity of a hepatotoxic agent, thioacetamide, compared the NSO and NAC liver preventive effects in experimental animal model. Wistar-albino rats were randomly allocated to five groups, each consisting of eight rats, and were subjected to different treatment regimens for 6 days. Alanine aminotransferase (ALT), malondialdehyde (MDA), and protein carbonyl (PC) levels decreased significantly by NSO treatment (P [Med-Science 2017; 6(1.000): 96-103]

Details

Language :
English
ISSN :
21470634
Volume :
6
Issue :
1
Database :
OpenAIRE
Journal :
Medicine Science
Accession number :
edsair.doi.dedup.....03eac780f6b973ac12712f5c21061acb