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Multi-spectral laser speckle contrast images using a wavelength-swept laser
- Source :
- Journal of Biomedical Optics
- Publication Year :
- 2019
- Publisher :
- SPIE-Intl Soc Optical Eng, 2019.
-
Abstract
- A multi-spectral laser speckle contrast imaging (MS-LSCI) system is proposed using only a single wavelength-swept laser, which provides both highly coherent and multi-spectral outputs to simultaneously generate laser speckle contrast images and multi-spectral images, respectively. Using a laser light swept from 770 to 821 nm at a repetition rate of 5 Hz and a CCD camera of 335 fps, 67 multi-spectral frame images are acquired in 0.76 nm wavebands over 51 nm spectral range. The spectral sub-windowing method of single wavelength-swept laser source is used to solve the lack of spectral information from a few individual light sources, which is a limitation of conventional MS-LSCI systems. In addition to the speckle flow index from the LSCI frames, the multi-spectrally encoded images can generate additional images of spectral absorbance. To further examine the performance of the MS-LSCI system, an in vivo cuff-induced ischemia experiment was conducted to show the real-time imaging of hemodynamic and blood oxygen saturation changes simultaneously over the entire 2.5 cm×4.5 cm field of view.
- Subjects :
- Paper
Materials science
media_common.quotation_subject
Multispectral image
Biomedical Engineering
multi-spectral imaging
Field of view
01 natural sciences
Imaging
law.invention
Fingers
010309 optics
Biomaterials
Speckle pattern
Optics
Signal-to-noise ratio
Ischemia
law
0103 physical sciences
Image Processing, Computer-Assisted
Humans
Contrast (vision)
media_common
laser speckle imaging
Phantoms, Imaging
business.industry
Lasers
Optical Imaging
Hemodynamics
Laser Speckle Imaging
Laser
Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Oxygen
Wavelength
Oxyhemoglobins
Feasibility Studies
wavelength-swept laser
business
Subjects
Details
- ISSN :
- 10833668
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Journal of Biomedical Optics
- Accession number :
- edsair.doi.dedup.....03f012429c15a1eee85f83546bbab9a4