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Immunothrombosis: Molecular Aspects and New Therapeutic Perspectives

Authors :
María Marcos-Jubilar
Ramón Lecumberri
José A. Páramo
Source :
Journal of Clinical Medicine. 12:1399
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy. The purpose of this review is to provide an overview of the current data regarding the mechanisms involved in immunothrombosis in order to understand the new therapeutic strategies focused in reducing thrombotic risk by controlling the inflammation.

Details

ISSN :
20770383
Volume :
12
Database :
OpenAIRE
Journal :
Journal of Clinical Medicine
Accession number :
edsair.doi.dedup.....0401500a53af21193f5730148af4f699
Full Text :
https://doi.org/10.3390/jcm12041399