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Development and assessment of a modified Pediatric Crohn Disease Activity Index
- Source :
- Journal of pediatric gastroenterology and nutrition. 51(2)
- Publication Year :
- 2010
-
Abstract
- The Pediatric Crohn Disease Activity Index (PCDAI) is an established and validated measure of disease activity in children with Crohn disease. However, its use in the research setting can be limited because of ambiguity of the subjective and anthropometric components of the index. Here we propose and evaluate a modified PCDAI (Mod PCDAI) consisting of the laboratory measures of the PCDAI plus C-reactive protein. This Mod PCDAI can provide an indication of disease activity because it correlates with the PCDAI, physicians' global assessment, and fecal calprotectin, and therefore may provide a suitable alternative to the PCDAI when required.
- Subjects :
- medicine.medical_specialty
Adolescent
Crohn disease
business.industry
Gastroenterology
Pediatrics
Severity of Illness Index
Crohn disease activity index
Disease activity
Feces
C-Reactive Protein
Crohn Disease
Internal medicine
Pediatrics, Perinatology and Child Health
Severity of illness
medicine
Humans
Calprotectin
business
Child
Research setting
Leukocyte L1 Antigen Complex
Biomarkers
Subjects
Details
- ISSN :
- 15364801
- Volume :
- 51
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of pediatric gastroenterology and nutrition
- Accession number :
- edsair.doi.dedup.....046e94c9b5533d8daa4abb99f366b272