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Potential of breastmilk in stem cell research
- Source :
- Cell and tissue banking. 20(4)
- Publication Year :
- 2018
-
Abstract
- Breastmilk is a dynamic, multi-faceted, and complex fluid containing a plethora of biochemical and cellular components that execute developmental effects or differentiation program, providing nourishment and immunity to newborns. Recently, it was reported that breastmilk contains a heterogeneous population of naive cells, including pluripotent stem cells, multipotent stem cells, immune cells, and non-immune cells. The stem cells derived from breastmilk possess immune privilege and non-tumorigenic properties. Thus, breastmilk may represent an ideal source of stem cells collected by non-perceive procedure than other available sources. Thus, this "maternally originating natural regenerative medicine" may have innumerable applications in clinical biology, cosmetics, and pharmacokinetics. This review describes the efficient integrated cellular system of mammary glands, the impressive stem cell hierarchy of breastmilk, and their possible implications in translational research and therapeutics.
- Subjects :
- Pluripotent Stem Cells
Biomedical Engineering
Biology
Regenerative Medicine
Regenerative medicine
Biomaterials
03 medical and health sciences
0302 clinical medicine
Immune system
Immune privilege
Immunity
Humans
Induced pluripotent stem cell
Mammary Glands, Human
030222 orthopedics
Transplantation
Immunity, Cellular
Milk, Human
Multipotent Stem Cells
Infant, Newborn
Cell Differentiation
Cell Biology
Stem Cell Research
Cell biology
Heterogeneous population
Multipotent Stem Cell
030221 ophthalmology & optometry
Stem cell
Subjects
Details
- ISSN :
- 15736814
- Volume :
- 20
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Cell and tissue banking
- Accession number :
- edsair.doi.dedup.....04fc82b51aa3356f3f909daf1b9e1c14