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Prognostic Value of Continuous Electroencephalogram Delta Power in Neonates With Hypoxic-Ischemic Encephalopathy

Authors :
Srinivas Kota
Adre J. du Plessis
Taeun Chang
Tareq Al-Shargabi
An N. Massaro
Caitlin Cristante
Rathinaswamy B. Govindan
Gilbert Vezina
Source :
J Child Neurol
Publication Year :
2020
Publisher :
SAGE Publications, 2020.

Abstract

The objective was to examine the discriminatory ability of electroencephalogram (EEG) delta power in neonates with hypoxic-ischemic encephalopathy (HIE) with well-defined outcomes. Prolonged continuous EEG recordings from term neonates with HIE during therapeutic hypothermia enrolled in a prospective observational study were examined. Adverse outcome was defined as death or severe brain injury by magnetic resonance imaging (MRI); favorable outcome was defined as normal or mild injury by MRI. Neonates were stratified by Sarnat grade of encephalopathy at admission. EEG was partitioned into 10-minute nonoverlapping artifact- and seizure-free epochs. Delta power was calculated and compared between the groups using receiver operating characteristic (ROC) analyses and Wilcoxon rank-sum tests. An area under the ROC curve >0.7 with P

Details

ISSN :
17088283 and 08830738
Volume :
35
Database :
OpenAIRE
Journal :
Journal of Child Neurology
Accession number :
edsair.doi.dedup.....0524a84dcc67ab0e80c75c6f2ab77a00
Full Text :
https://doi.org/10.1177/0883073820915323