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Ethnic variation of oral microbiota in children
- Source :
- Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020), Scientific Reports
- Publication Year :
- 2020
- Publisher :
- Nature Publishing Group, 2020.
-
Abstract
- Despite widely used preventive measures such as sealant programs to control caries prevalence, disparities are seen among ethnic groups. Supragingival plaque harbors hundreds of bacterial species, playing a significant role in oral health and disease. It is unknown whether the ethnic variation influences the supragingival microbiota in children. In our study, variations in microbiota of the supragingival plaque was investigated from 96 children between 6 and 11 years old in four ethnic groups (African American, Burmese, Caucasian, and Hispanic) from the same geographic location by 16S rRNA gene sequencing. We found that the microbial alpha and beta diversity of supragingival microbiota significantly differed between ethnic groups. The supragingival plaque microbiota had the most complex microbial community in Burmese children. Within-group microbiota similarity in Burmese or Caucasian children was significantly higher than between-groups similarity. We identified seven ethnic group-specific bacterial taxa after adjusting for dental plaque index, decayed missing filled teeth (DMFT) and the frequency of brushing. Children with high plaque index and high DMFT values were more similar to each other in the overall microbial community, compared to low plaque index or low DMFT groups in which inter-subject variation is high. Several bacterial taxa associated with high plaque index or high DMFT were ethnic group-specific. These results demonstrated that supragingival microbiota differed among ethnicity groups in children.
- Subjects :
- Male
0301 basic medicine
Plaque index
Dental Plaque
Ethnic group
lcsh:Medicine
Oral Health
Dental Caries
Oral health
Biology
Article
03 medical and health sciences
Oral Microbiota
0302 clinical medicine
RNA, Ribosomal, 16S
Ethnicity
Humans
Oral diseases
Child
Saliva
Author Correction
lcsh:Science
African american
Multidisciplinary
Bacteria
Microbiota
lcsh:R
Caries prevalence
030206 dentistry
United States
Dental Plaque Index
stomatognathic diseases
030104 developmental biology
16s rrna gene sequencing
Female
lcsh:Q
Microbiome
Demography
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....0534aa00dee987cb5f06a87e7775a1da