Complete atrioventricular block induced by rituximab in monotherapy in an aged patient with non-Hodgkin’s diffuse large B-cell lymphoma

Authors :: Esquerdo Galiana G
Juárez Marroquí A
Llorca Ferrándiz C
Cervera Grau Jm
Maciá Escalante S
Belso Candela A
Source :: Clinical and Translational Oncology. 10:298-299
Publication Year :: 2008
Publisher :: Springer Science and Business Media LLC, 2008.
Abstract: Rituximab is a treatment option to non-Hodg kin's diffuse large B-cell lymphoma (NHDLBCL) in advanced stage and comorbility. It is known the cardiotoxicity effect of this drug, but there is no previous report describing a complete atrioventricular block (CAVB) secundary to treatment with Rituximab. We present an elderly woman treated with monotherapy with Rituximab who experienced a CAVB after administration of the fifth dose of this drug.

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