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Emerging roles for AQP in mammalian extracellular vesicles

Authors :
Charlotte Clarke-Bland
Andrew Devitt
Roslyn M. Bill
Source :
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1864:183826
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

Recent research in the aquaporin (AQP) field has identified a role for diverse AQPs in extracellular vesicles (EV). Though still in its infancy, there is a growing body of knowledge in the area; AQPs in EV have been suggested as biomarkers for disease, as drug targets and show potential as therapeutics. To advance further in this field, AQPs in EV must be better understood. Here we summarize current knowledge of the presence and function of AQPs in EV and hypothesise their roles in health and disease.

Details

ISSN :
00052736 and 18792642
Volume :
1864
Database :
OpenAIRE
Journal :
Biochimica et Biophysica Acta (BBA) - Biomembranes
Accession number :
edsair.doi.dedup.....056cf1f361105fd8a07fbab73b4e713a
Full Text :
https://doi.org/10.1016/j.bbamem.2021.183826