Back to Search
Start Over
Silver-Catalyzed C-H Aryloxydifluoromethylation and Arylthiodifluoromethylation of Heteroarenes
- Source :
- Organic letters. 22(14)
- Publication Year :
- 2020
-
Abstract
- The oxidative C-H aryloxydifluoromethylation and arylthiodifluoromethylation of heteroaromatic compounds through the decarboxylation of easily accessible aryloxydifluoroacetic acids and arylthiodifluoroacetic acids, respectively, are disclosed. These reactions are promoted by the combination of catalytic AgNO3 and Selectfluor or K2S2O8 to give ArOCF2- and ArSCF2-substituted heteroaromatic compounds in moderate to high yields.
Details
- ISSN :
- 15237052
- Volume :
- 22
- Issue :
- 14
- Database :
- OpenAIRE
- Journal :
- Organic letters
- Accession number :
- edsair.doi.dedup.....05c8a93cc1bb4a76d0688d32d502b429