Alternate Day Steroid Therapy in Diffuse Pulmonary Sarcoidosis

Four patients with diffuse pulmonary sarcoidosis were treated with alternate-day corticosteroid therapy. Prompt resolution of physiologic, radiologic and symptomatic evidence of disease occurred without significant side-effects of therapy. While corticosteroid therapy may not alter the longterm prognosis in sarcoidosis, prompt complete remission can be induced safely with an alternate day regimen. Such therapy is advised for acute, symptomatic pulmonary involvement.