Back to Search
Start Over
Immunohistochemical Characterization of Leukocytic Subpopulations in Chronic Endometritis
- Source :
- Infectious Diseases in Obstetrics and Gynecology, Vol 4, Iss 5, Pp 287-293 (1996), Infectious Diseases in Obstetrics and Gynecology
- Publication Year :
- 1996
- Publisher :
- Hindawi Limited, 1996.
-
Abstract
- Objective: We analyzed the histologic and immunohistochemical changes in the endometrial leukocytic subpopulations to determine which of them are characteristic of chronic endometritis. Results: Endometrial biopsies from 25 cases of chronic endometritis and 35 controls were studied. Characteristic morphologic findings included the presence of a plasma cell infiltrate, and a prominent, albeit non-specific, lymphocytic infiltrate in all patients with endometritis. A neutrophilic infiltrate was also noted in 90% of the patients. Other non-specific histologic findings included occasional prominent lymphoid aggregates, stromal edema, hemorrhage, and necrosis and cystic dilation of some glands in endometria of patients with chronic endometritis. Endometrial immune cells were investigated immunohistochemically using antibodies to CD3 (pan-T), CD20 (pan-B, L26), and Ham-56 (macrophage). In control patients, endometrial immune cells were predominantly composed of CD3 and Ham-56 positive cells. CD20 positive cells comprised
- Subjects :
- Pathology
medicine.medical_specialty
business.industry
Obstetrics and Gynecology
Dermatology
lcsh:Gynecology and obstetrics
lcsh:Infectious and parasitic diseases
Infectious Diseases
Immunology
Medicine
Immunohistochemistry
lcsh:RC109-216
sense organs
business
Chronic Endometritis
skin and connective tissue diseases
lcsh:RG1-991
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 10980997 and 10647449
- Volume :
- 4
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Infectious Diseases in Obstetrics and Gynecology
- Accession number :
- edsair.doi.dedup.....06834e8e2f096898d35fa1a307edae41