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Incidence of hepatitis D virus infection in Japanese patients with hepatocellular carcinoma--immunohistochemical investigation of the delta antigen
- Source :
- The Kurume medical journal. 39(4)
- Publication Year :
- 1992
-
Abstract
- In order to clarify the incidence of the delta agent among hepatocellular carcinomas (HCCs) in Kurume, where the hepatitis B infection and its related HCC are most prevalent in Japan, liver tissues from sero hepatitis B surface antigen-positive autopsy cases, with or without HCC, were immunohistochemically investigated for detection of the delta antigen. Only one patient (1.7%) among 58 patients with HCC was found to have delta-antigen in the nuclei in the hepatocytes, which were diffusely distributed throughout the non-cancerous liver. None of 26 patients with liver cirrhosis showed delta-antigen in the liver tissue. The incidence is so low that the delta agent is unlikely to have a role in the development of HCC in our areas.
- Subjects :
- Male
medicine.medical_specialty
Pathology
Cirrhosis
Carcinoma, Hepatocellular
Autopsy
Gastroenterology
Immunoenzyme Techniques
Japan
Internal medicine
Prevalence
Medicine
Humans
neoplasms
Antigens, Viral
Retrospective Studies
Hepatitis delta Antigens
Delta Antigen
business.industry
Incidence (epidemiology)
Incidence
Liver Neoplasms
General Medicine
HCCS
Hepatitis B
Middle Aged
medicine.disease
digestive system diseases
Hepatitis D
Hepatocellular carcinoma
Immunohistochemistry
Female
Hepatitis Delta Virus
business
Subjects
Details
- ISSN :
- 00235679
- Volume :
- 39
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- The Kurume medical journal
- Accession number :
- edsair.doi.dedup.....0684333df178eaa6528e215b53473b65