Back to Search
Start Over
Measurement of central corneal thickness by high-resolution Scheimpflug imaging, Fourier-domain optical coherence tomography and ultrasound pachymetry
- Source :
- Acta Ophthalmologica. 90:449-455
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- Purpose: To compare the repeatability and reproducibility of central corneal thickness (CCT) measurements by high-resolution (HR) rotating Scheimpflug imaging and Fourier-domain optical coherence tomography (FD-OCT). CCT measurements were compared to those determined by ultrasound pachymetry (UP). Methods: In 35 healthy eyes, intra-observer repeatability for HR Scheimpflug (Pentacam) and FD-OCT (RTVue) systems was determined in consecutive images taken by an observer in the shortest time possible. Imaging was repeated again by a second observer to evaluate inter-observer reproducibility. The CCT measurements were compared among Scheimpflug, FD-OCT and UP images. Results: Mean coefficients of repeatability were 0.48% for Scheimpflug and 0.26% for FD-OCT. For Scheimpflug, the coefficient of inter-operator reproducibility was 0.87%. For FD-OCT, the coefficient of inter-operator reproducibility was 0.45%. The CCT measurements by Scheimpflug, OCT and UP images were (mean ± standard deviation) 521.7 ± 27.6 μm, 510.8 ± 28.6 μm and 516.5 ± 27.6 μm, respectively. The differences between instruments were statistically significant. The 95% limits of agreement in CCT were −0.7 to 22.5 μm for Pentacam-OCT, −13.4 to 24.0 μm for Pentacam-UP and −26.7 to 15.4 μm for OCT-UP. There was a high degree of correlation between CCT measured by all 3 methods. Conclusion: Noncontact measurements of CCT with HR Scheimpflug and FD-OCT systems yielded excellent repeatability and reproducibility and can be used interchangeably. Although both devices were comparable with UP; in clinical practice, the measurements acquired by optical modalities are not directly interchangeable with UP measurements.
- Subjects :
- Adult
Male
Materials science
Adolescent
Corneal Pachymetry
genetic structures
Scheimpflug principle
High resolution
Cornea
Young Adult
Optics
Optical coherence tomography
Reference Values
Photography
medicine
Humans
Prospective Studies
Fourier domain
Observer Variation
Reproducibility
Fourier Analysis
medicine.diagnostic_test
business.industry
Reproducibility of Results
Ultrasound pachymetry
Organ Size
General Medicine
Repeatability
eye diseases
Ophthalmology
Female
sense organs
Tomography
business
Tomography, Optical Coherence
Biomedical engineering
Subjects
Details
- ISSN :
- 1755375X
- Volume :
- 90
- Database :
- OpenAIRE
- Journal :
- Acta Ophthalmologica
- Accession number :
- edsair.doi.dedup.....06f058c16a2ca37540e4b4bcb4cf5f13