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Resveratrol: A medical drug for acute pancreatitis

Authors :
Qing-Yong Ma
Zhen-Hua Ma
Source :
World Journal of Gastroenterology. 11:3171
Publication Year :
2005
Publisher :
Baishideng Publishing Group Inc., 2005.

Abstract

Accumulating evidence demonstrates that resveratrol, a natural polyphenolic compound extracted from plants, inhibit inflammation when administered. It has direct effects on suppression of platelet coagulation and cytokines production in many experimental models. Because microcirculation occlusion and cytokines over-production is involved in many diseases such as acute pancreatitis (AP), the discovery of resveratrol as platelet and cytokines inhibitors has shed light on the treatment of AP, which still has significant mortality and morbidity. It is anticipated that this natural polyphenol could serve as a therapeutic compound in managing AP through different pathways.

Details

ISSN :
10079327
Volume :
11
Database :
OpenAIRE
Journal :
World Journal of Gastroenterology
Accession number :
edsair.doi.dedup.....07193d730348c13ed8440a38545c9848