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Relationship Between Enterococcus faecalis Infective Endocarditis and Colorectal Neoplasm: Preliminary Results From a Cohort of 154 Patients
- Source :
- Revista Española de Cardiología (English Edition). 70:451-458
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Introduction and objectives The association between Streptococcus bovis group infective endocarditis and colorectal neoplasm (CRN) is well-known. However, no studies have assessed the association between Enterococcus faecalis infective endocarditis (EFIE) and CRN. We aimed to determine whether the prevalence of CRN is higher in patients with EFIE and an unclear source of infection than in patients with EFIE and a known source of infection or in the general population. Methods Retrospective analysis of a cohort of 154 patients with definite EFIE (109 with an unclear source of infection and 45 with an identified source) from 2 Spanish teaching hospitals to determine the prevalence of CRN and other colorectal diseases. Results In the group with an unknown source of infection, 61 patients (56%) underwent colonoscopy; of these, 31 (50.8%) had CRN. Nonadvanced colorectal adenoma was detected in 22 patients (36%), advanced adenoma in 5 (8.2%), and colorectal carcinoma (CRC) in 4 (6.6%). Among patients who survived the EFIE episode with ≥ 2 years of follow-up, 1 case of CRC was subsequently diagnosed. Only 6 patients (13.3%) with an identified focus of infection underwent colonoscopy; 1 of these patients (16.7%) was diagnosed with CRN. The prevalence of adenomas was slightly higher than that of the Spanish population in the same age range, whereas that of CRC was 17-fold higher. Conclusions CRN was found in more than half of patients with EFIE and an unclear focus of infection who underwent colonoscopy. Colonoscopy should be recommended in patients with EFIE and an unclear source of infection.
- Subjects :
- Male
medicine.medical_specialty
Epidemiology
Colorectal cancer
Population
Colonoscopy
610 Medicine & health
Colorectal adenoma
030204 cardiovascular system & hematology
2705 Cardiology and Cardiovascular Medicine
03 medical and health sciences
0302 clinical medicine
Internal medicine
Enterococcus faecalis
Prevalence
medicine
Humans
Endocarditis
030212 general & internal medicine
education
Gram-Positive Bacterial Infections
Aged
Retrospective Studies
education.field_of_study
medicine.diagnostic_test
biology
business.industry
Endocarditis, Bacterial
General Medicine
Middle Aged
medicine.disease
Streptococcus bovis
biology.organism_classification
10020 Clinic for Cardiac Surgery
Surgery
Spain
Infective endocarditis
Cohort
Female
Colorectal Neoplasms
business
Colorectal disease
Follow-Up Studies
Subjects
Details
- ISSN :
- 18855857
- Volume :
- 70
- Database :
- OpenAIRE
- Journal :
- Revista Española de Cardiología (English Edition)
- Accession number :
- edsair.doi.dedup.....0723eb921e6d9ab99df063e12d38ffb5