Inclusion body myositis and HIV infection

A 56 year-old French man was diagnosed as having HIV infec-tion in 2000. Initially the CD4 cell counts were 314 and the viral load was 626 copies. A treatment with HAART was started. Two months later the CD4 was normal and the viral load fell to 0. One year later he noticed difficulty in climbing stairs with slowly progression and in seven months he could walk only with aids of canes. He also noticed some difficulties with movements of the hands. A diagnostic of a muscle disease due to zidovudine was done and HAART was stopped. As there was no improvement in