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Traumatic injury and atrial fibrillation among deployed service members
- Source :
- Journal of Cardiovascular Electrophysiology. 32:2590-2594
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- INTRODUCTION Atrial fibrillation and atrial flutter (AF/AFL), the most common atrial arrhythmias, have never been examined in combat casualties. In this study, we investigated the impact of traumatic injury on AF/AFL among service members with deployment history. METHODS Sampled from the Department of Defense (DoD) Trauma Registry (n = 10,000), each injured patient in this retrospective cohort study was matched with a non-injured service member drawn from the Veterans Affairs/DoD Identity Repository. The primary outcome was AF/AFL diagnosis identified using ICD-9-CM and ICD-10-CM codes. Competing risk regressions based on Fine and Gray subdistribution hazards model with were utilized to assess the association between injury and AF/AFL. RESULTS There were 130 reported AF/AFL cases, 90 of whom were injured and 40 were non-injured. The estimated cumulative incidence rates of AF/AFL for injured was higher compared to non-injured patients (hazards ratio [HR] = 2.04; 95% confidence interval [CI] = 1.44, 2.87). After adjustment demographics and tobacco use, the association did not appreciably decrease (HR = 1.90; 95% CI = 1.23, 2.93). Additional adjustment for obesity, hypertension, diabetes, and vascular disorders, the association between injury and AF/AFL was no longer statistically significant (HR = 1.51; 95% CI = 0.99, 2.52). CONCLUSION Higher AF/AFL incidence rate was observed among deployed service members with combat injury compared to servicemembers without injury. The association did not remain significant after adjustment for cardiovascular-related covariates. These findings highlight the need for combat casualty surveillance to further understand the AF/AFL risk within the military population and to elucidate the potential underlying pathophysiologic mechanisms.
- Subjects :
- Fibrillation
medicine.medical_specialty
education.field_of_study
business.industry
Incidence
Hazard ratio
Population
Retrospective cohort study
Atrial fibrillation
medicine.disease
Atrial Flutter
Physiology (medical)
Internal medicine
Atrial Fibrillation
Humans
Medicine
Cumulative incidence
medicine.symptom
Cardiology and Cardiovascular Medicine
business
education
Veterans Affairs
Atrial flutter
Proportional Hazards Models
Retrospective Studies
Subjects
Details
- ISSN :
- 15408167 and 10453873
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Journal of Cardiovascular Electrophysiology
- Accession number :
- edsair.doi.dedup.....078c74624d900a06270836e3164d6138