The Role of HLA-Driven Viral Adaptation in Immune Control of HIV Infection in a Maternal Population in Durban, South Africa

Authors :: Hempenstall, A
Muenchhoff, M
Adland, E
Singh, S
Carlqvist, A
Ndung'u, T
Goulder, P
Source :: 18th Symposium on Infections in the Immunocompromised Host; 20140615-20140617; Berlin; DOC14ichs12 /20140603/
Publication Year :: 2014
Publisher :: German Medical Science GMS Publishing House, 2014.
Abstract: HLA-restricted Cytotoxic T-lymphocytes that are capable of suppressing HIV replication exert a strong pressure on the virus favoring the selection of escape mutations. Protective HLA molecules drive the selection of escape mutants that reduce viral replicative capacity. Transmission of viruses with [for full text, please go to the a.m. URL]<br />18th Symposium on Infections in the Immunocompromised Host

Language :: English
Database :: OpenAIRE
Journal :: 18th Symposium on Infections in the Immunocompromised Host; 20140615-20140617; Berlin; DOC14ichs12 /20140603/
Accession number :: edsair.doi.dedup.....07e1fba40c116e21f88f670c70014ac5
Full Text :: https://doi.org/10.3205/14ichs12

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