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Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

Authors :
Elizabeth M. Johnson
Mahmoud A. Ghannoum
Michael R. Yeaman
Carol A. Munro
Patrick Van Dijck
Jeniel E. Nett
Dominique Sanglard
Richard Calderone
Leah E. Cowen
Johan Maertens
Maiken Cavling Arendrup
Axel A. Brakhage
Judith Berman
Katrien Lagrou
Christophe d'Enfert
Karin Thevissen
Paul Cos
Gordon Ramage
Jelmer Sjollema
Tom Coenye
Isabel Spriet
Paul E. Verweij
Jose L. Lopez-Ribot
Ana Espinel-Ingroff
Sebastian A. J. Zaat
Emilia Cantón
Mary Ann Jabra-Rizk
David R. Andes
Neil A. R. Gow
Scott G. Filler
Mira Edgerton
Maurizio Sanguinetti
Michael A. Pfaller
Joost Wauters
Bruno P. A. Cammue
Clarissa J. Nobile
Hubertus Haas
Adilia Warris
Shawn R. Lockhart
Van Dijck, Patrick
Sjollema, Jelmer
Thevissen, Karin
Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven)
University Medical Center Groningen [Groningen] (UMCG)
Vlaams Instituut voor Biotechnologie [Ghent, Belgique] (VIB)
Center for Plant Systems Biology (PSB Center)
Tel Aviv University [Tel Aviv]
Biologie et Pathogénicité fongiques
Institut Pasteur [Paris]-Institut National de la Recherche Agronomique (INRA)
University of Wisconsin-Madison
Statens Serum Institut [Copenhagen]
Rigshospitalet [Copenhagen]
Copenhagen University Hospital
University of Copenhagen = Københavns Universitet (KU)
Leibniz Institute for Natural Product Research and Infection Biology (Hans Knoell Institute)
Friedrich-Schiller-Universität = Friedrich Schiller University Jena [Jena, Germany]
Georgetown University Medical Center
Medical Research Institute La Fe
Partenaires INRAE
Universiteit Gent = Ghent University [Belgium] (UGENT)
ESCMID [Basel]
University of Antwerp (UA)
University of Toronto
University at Buffalo [SUNY] (SUNY Buffalo)
State University of New York (SUNY)
Virginia Commonwealth University (VCU)
Harbor UCLA Medical Center [Torrance, Ca.]
University Hospitals of Cleveland
Case Western Reserve University [Cleveland]
University of Aberdeen
Innsbruck Medical University [Austria] (IMU)
University of Maryland [Baltimore]
Public Health England
Centers for Disease Control and Prevention [Atlanta] (CDC)
Centers for Disease Control and Prevention
The University of Texas at San Antonio (UTSA)
UZ Leuven
University of California [Merced]
University of California
University of Iowa [Iowa City]
JMI Laboratories
University of Glasgow
Université de Lausanne (UNIL)
Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV)
Università cattolica del Sacro Cuore [Roma] (Unicatt)
Radboud university [Nijmegen]
Univ Aberdeen, Aberdeen Fungal Grp, MRC Ctr Med Mycol, Foresterhill, Aberdeen, Scotland
University Hospitals Leuven [Leuven]
Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC)
University of Amsterdam [Amsterdam] (UvA)
Industrial Research Fund [IOFm/05/022]
Israel Science Foundation [314/13]
Wellcome Trust
MRC
Agence Nationale de Recherche [ANR-10-LABX-62-IBEID]
National Institutes of Health [R35GM124594, R21AI125801]
Wellcome Trust Strategic Award [097377]
MRC Centre for Medical Mycology at the University of Aberdeen [MR/N006364/1]
Astellas
Basilea
Gilead
MSD
NovaBiotics
Pfizer
T2Biosystems
F2G
Cidara
Amplyx
MRC [MR/N006364/1]
FWO [FWO WO.009.16N].
ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010)
European Project: 340087,EC:FP7:ERC,ERC-2013-ADG,RAPLODAPT(2014)
Tel Aviv University (TAU)
Biologie et Pathogénicité fongiques (BPF)
Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris] (IP)
University of Copenhagen = Københavns Universitet (UCPH)
Universiteit Gent = Ghent University (UGENT)
Innsbruck Medical University = Medizinische Universität Innsbruck (IMU)
Universitair Ziekenhuis Leuven (UZ Leuven)
University of California [Merced] (UC Merced)
University of California (UC)
Université de Lausanne = University of Lausanne (UNIL)
Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart [Roma] (Unicatt)
Radboud University [Nijmegen]
Source :
Microbial cell (Graz, Austria), vol 5, iss 7, Microbial Cell 7 (5), 300-326. (2018), MICROBIAL CELL, r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe, instname, Microbial Cell, 5, 7, pp. 300-326, Microbial Cell, Microbial Cell, Shared Science Publishers OG, 2018, 5 (7), pp.300-326. ⟨10.15698/mic2018.07.638⟩, Microbial cell, Van Dijck, P; Sjollema, J; Cammue, BP; Lagrou, K; Berman, J; d'Enfert, C; et al.(2018). Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.. Microbial cell (Graz, Austria), 5(7), 300-326. doi: 10.15698/mic2018.07.638. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9zn0q5r0, Van Dijck, P, Sjollema, J, Cammue, B P, Lagrou, K, Berman, J, d'Enfert, C, Andes, D R, Arendrup, M C, Brakhage, A A, Calderone, R, Cantón, E, Coenye, T, Cos, P, Cowen, L E, Edgerton, M, Espinel-Ingroff, A, Filler, S G, Ghannoum, M, Gow, N A R, Haas, H, Jabra-Rizk, M A, Johnson, E M, Lockhart, S R, Lopez-Ribot, J L, Maertens, J, Munro, C A, Nett, J E, Nobile, C J, Pfaller, M A, Ramage, G, Sanglard, D, Sanguinetti, M, Spriet, I, Verweij, P E, Warris, A, Wauters, J, Yeaman, M R, Zaat, S A J & Thevissen, K 2018, ' Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms ', Microbial Cell Factories, vol. 5, no. 7, pp. 300-326 . https://doi.org/10.15698/mic2018.07.638, Microbial Cell, 2018, 5 (7), pp.300-326. ⟨10.15698/mic2018.07.638⟩, Microbial Cell, Vol 5, Iss 7, Pp 300-326 (2018), Microbial Cell, 5, 300-326
Publication Year :
2018

Abstract

Contains fulltext : 196638.pdf (Publisher’s version ) (Open Access) Unlike superficial fungal infections of the skin and nails, which are the most common fungal diseases in humans, invasive fungal infections carry high morbidity and mortality, particularly those associated with biofilm formation on indwelling medical devices. Therapeutic management of these complex diseases is often complicated by the rise in resistance to the commonly used antifungal agents. Therefore, the availability of accurate susceptibility testing methods for determining antifungal resistance, as well as discovery of novel antifungal and antibiofilm agents, are key priorities in medical mycology research. To direct advancements in this field, here we present an overview of the methods currently available for determining (i) the susceptibility or resistance of fungal isolates or biofilms to antifungal or antibiofilm compounds and compound combinations; (ii) the in vivo efficacy of antifungal and antibiofilm compounds and compound combinations; and (iii) the in vitro and in vivo performance of anti-infective coatings and materials to prevent fungal biofilm-based infections.

Subjects

Subjects :
0301 basic medicine
diagnosis
[SDV]Life Sciences [q-bio]
LIPOSOMAL
lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]
Applied Microbiology and Biotechnology
immune response
biofilm
High morbidity
transcriptomics
MINIMUM FUNGICIDAL
CONCENTRATIONS
Amphotericin B
eradication
Medicine
GUINEA-PIG MODEL
LIPOSOMAL AMPHOTERICIN-B
lcsh:QH301-705.5
AMPHOTERICIN-B
antibiofilm material coating, antifungal susceptibility testing, biofilm eradication, biofilm inhibition, in vivo models
antifungal susceptibility testing
biofilm inhibition
biofilm eradication
antibiofilm material coating
in vivo models
3. Good health
CANDIDA-ALBICANS BIOFILMS
GALLERIA-MELLONELLA
Infectious Diseases
tuberculosis
5.1 Pharmaceuticals
HUMAN-PATHOGENIC FUNGI
Development of treatments and therapeutic interventions
Infection
Fungal biofilm
Life Sciences & Biomedicine
VULVO-VAGINAL CANDIDIASIS
medicine.drug
Antifungal
latent infection
Medical mycology
medicine.drug_class
OXYSPORUM SPECIES COMPLEX
030106 microbiology
INVASIVE PULMONARY ASPERGILLOSIS
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Microbiology
GALLERIA-MELLONELLA LARVAE
03 medical and health sciences
proteomics
In vivo
Virology
Genetics
Molecular Biology
Biology
Science & Technology
business.industry
LARVAE
Biofilm
Biology and Life Sciences
Cell Biology
In vitro
Emerging Infectious Diseases
Good Health and Well Being
lcsh:Biology (General)
point-of-care
Parasitology
MINIMUM FUNGICIDAL CONCENTRATIONS
Human medicine
Antimicrobial Resistance
RAT SUBCUTANEOUS MODEL
business

Details

ISSN :
23112638
Database :
OpenAIRE
Journal :
Microbial cell (Graz, Austria), vol 5, iss 7, Microbial Cell 7 (5), 300-326. (2018), MICROBIAL CELL, r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe, instname, Microbial Cell, 5, 7, pp. 300-326, Microbial Cell, Microbial Cell, Shared Science Publishers OG, 2018, 5 (7), pp.300-326. ⟨10.15698/mic2018.07.638⟩, Microbial cell, Van Dijck, P; Sjollema, J; Cammue, BP; Lagrou, K; Berman, J; d'Enfert, C; et al.(2018). Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.. Microbial cell (Graz, Austria), 5(7), 300-326. doi: 10.15698/mic2018.07.638. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9zn0q5r0, Van Dijck, P, Sjollema, J, Cammue, B P, Lagrou, K, Berman, J, d'Enfert, C, Andes, D R, Arendrup, M C, Brakhage, A A, Calderone, R, Cantón, E, Coenye, T, Cos, P, Cowen, L E, Edgerton, M, Espinel-Ingroff, A, Filler, S G, Ghannoum, M, Gow, N A R, Haas, H, Jabra-Rizk, M A, Johnson, E M, Lockhart, S R, Lopez-Ribot, J L, Maertens, J, Munro, C A, Nett, J E, Nobile, C J, Pfaller, M A, Ramage, G, Sanglard, D, Sanguinetti, M, Spriet, I, Verweij, P E, Warris, A, Wauters, J, Yeaman, M R, Zaat, S A J & Thevissen, K 2018, ' Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms ', Microbial Cell Factories, vol. 5, no. 7, pp. 300-326 . https://doi.org/10.15698/mic2018.07.638, Microbial Cell, 2018, 5 (7), pp.300-326. ⟨10.15698/mic2018.07.638⟩, Microbial Cell, Vol 5, Iss 7, Pp 300-326 (2018), Microbial Cell, 5, 300-326
Accession number :
edsair.doi.dedup.....07e5a8a83e382781126b376eb5ed2600
Full Text :
https://doi.org/10.15698/mic2018.07.638