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Successful treatment of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia
- Source :
- International journal of hematology. 97(3)
- Publication Year :
- 2012
-
Abstract
- The management of acute leukemia during pregnancy is challenging. Delays in treatment for acute leukemia can adversely affect maternal prognosis, but chemotherapy during pregnancy may induce severe adverse effects on the fetus. Here, we report a case of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+)ALL) who underwent remission induction therapy and successfully delivered a live infant after chemotherapy. The case is a 36-year-old woman diagnosed with Ph(+)ALL in the 27th week of pregnancy. She underwent remission induction therapy including daunorubicin, vincristine, cyclophosphamide, and prednisolone. Imatinib was not used in the induction therapy. She delivered the infant after one course of chemotherapy. The infant and the patient are both alive now, without any major complications.
- Subjects :
- Adult
Vincristine
medicine.medical_specialty
Pediatrics
Cyclophosphamide
medicine.medical_treatment
Prednisolone
Philadelphia chromosome
Pregnancy
hemic and lymphatic diseases
Remission Induction Therapy
Antineoplastic Combined Chemotherapy Protocols
medicine
Humans
Philadelphia Chromosome
Chemotherapy
Acute leukemia
business.industry
Daunorubicin
Remission Induction
Imatinib
Hematology
Induction Chemotherapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma
medicine.disease
Surgery
Female
business
Live Birth
Pregnancy Complications, Neoplastic
medicine.drug
Subjects
Details
- ISSN :
- 18653774
- Volume :
- 97
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- International journal of hematology
- Accession number :
- edsair.doi.dedup.....0824e8a16819ab1e50b64e803b7d9d90