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The quantified cell

Authors :
Ron Milo
Avi I. Flamholz
Rob Phillips
Source :
Molecular Biology of the Cell
Publication Year :
2014
Publisher :
American Society for Cell Biology (ASCB), 2014.

Abstract

The microscopic world of a cell can be as alien to our human-centered intuition as the confinement of quarks within protons or the event horizon of a black hole. We are prone to thinking by analogy—Golgi cisternae stack like pancakes, red blood cells look like donuts—but very little in our human experience is truly comparable to the immensely crowded, membrane-subdivided interior of a eukaryotic cell or the intricately layered structures of a mammalian tissue. So in our daily efforts to understand how cells work, we are faced with a challenge: how do we develop intuition that works at the microscopic scale?

Details

ISSN :
19394586 and 10591524
Volume :
25
Database :
OpenAIRE
Journal :
Molecular Biology of the Cell
Accession number :
edsair.doi.dedup.....084d9fe02f57ec5b8ead06c6f2a53b15
Full Text :
https://doi.org/10.1091/mbc.e14-09-1347