Supplementary Table 1 from Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival

Supp Tab 1 - Tissue samples used for this study were obtained from the Lester and Sue Smith Breast Cancer Tumor bank at Baylor College of Medicine. We studied 102 breast tumors from this bank that were collected from sites in the US and Europe. Study demographics define the majority of the population to be postmenopausal women, 97% Caucasian, and the median subject age to be 53 years. In this cohort, 95% of the tumors were invasive ductal carcinomas, 47% presented no lymph node involvement, all were without metastasis, and 76% of study participants had tumors {greater than or equal to}2cm3 at the time of diagnosis. The ER and PR status of each tissue sample was determined through immunohistochemistry (IHC) analysis, and HER2 status by fluorescent in-situ hybridization (FISH). This identified 49 ER-positive tumors and 53 triple-negative tumors. Of the ER-positive breast cancers, 12 tumors were also HER2-positive (24%), and 42 PR positive (86%).