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Chirality Sensing of α-Hydroxyphosphonates by N-tert-Butyl Sulfinyl Squaramide

Authors :
Jin-Pei Cheng
Xin Li
Cyndi Qixin He
Yao Li
K. N. Houk
Guo-Hui Yang
Source :
Organic letters. 19(16)
Publication Year :
2017

Abstract

N-tert-Butyl sulfinyl squaramides were used for chiral discrimination of α-hydroxyphosphonates using 31P NMR. A free energy relationship study indicates that both steric and the electronic effects influence the chiral recognition of the donors.

Details

ISSN :
15237052
Volume :
19
Issue :
16
Database :
OpenAIRE
Journal :
Organic letters
Accession number :
edsair.doi.dedup.....08bea7c8b0a06553333b5aee0f27a384