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Amorphous metal-organic frameworks for drug delivery
- Source :
- Chemical communications (Cambridge, England). 51(73)
- Publication Year :
- 2015
-
Abstract
- We report the encapsulation of the hydrophilic model molecule calcein in the Zr-based MOF UiO-66, followed by amorphization of the framework by ball-milling. We show controlled release of calcein over more than 30 days, compared with the 2 day release period from crystalline UiO-66.
- Subjects :
- Amorphous metal
Chemistry
technology, industry, and agriculture
Metals and Alloys
General Chemistry
Fluoresceins
Controlled release
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Calcein
chemistry.chemical_compound
Drug Delivery Systems
Chemical engineering
Coordination Complexes
Drug delivery
polycyclic compounds
Materials Chemistry
Ceramics and Composites
Humans
heterocyclic compounds
sense organs
Zirconium
Hydrophobic and Hydrophilic Interactions
HeLa Cells
Subjects
Details
- ISSN :
- 1364548X
- Volume :
- 51
- Issue :
- 73
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.doi.dedup.....08f32d2cb5de8fd7609739bb67a6a405