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Two novel MICA alleles, MICA*054 and MICA*056

Authors :
R Fernando
H. A. F Stephens
J. A. Madrigal
J. Grant
Ann-Margaret Little
Steven T. Cox
Source :
Tissue Antigens. 73:85-87
Publication Year :
2009
Publisher :
Wiley, 2009.

Abstract

We report the identification of two novel major histocompatibility complex (MHC) class I-related chain A (MICA) alleles. MICA*054 has a nucleotide substitution of A to G at position 871 (codon 268), encoding an amino acid change of serine to glycine in the alpha-3 domain. MICA*056 has a nucleotide substitution at position 758 of G to C resulting in the substitution of tryptophan for serine at codon 230, also in the alpha-3 domain.

Details

ISSN :
13990039 and 00012815
Volume :
73
Database :
OpenAIRE
Journal :
Tissue Antigens
Accession number :
edsair.doi.dedup.....09012d928d53679bd20e77892efcb879
Full Text :
https://doi.org/10.1111/j.1399-0039.2008.01173.x