Effects of thyroid dysfunction on hematological parameters: Case controlled study

Introduction The thyroid gland has a very important role in hematopoiesis, blood disorders are frequently seen in patients with thyroid disorders. Thyroid hormones have direct effect on blood parameters by stimulating erythrocytes precursors and indirectly by enhancing erythropoietin production. Patients and methods This is a case-control study which included 300 subjects who were grouped to 3 equal groups as a control, hypothyroidism, and hyperthyroidism groups. Patients with inherited or acquired red cell abnormalities, those receiving treatment for thyroid disorder or anemia, patient with chronic diseases, aged
Highlights • The thyroid gland has a very important role in hematopoiesis. • Females are more affected by thyroid disorders than males. • Thyroid hormones directly stimulate erythrocytes precursors and indirectly by enhancing erythropoietin production.