Supplementary Tables 1-3 and Supplementary Figures 1-4 from Genomic Profiling of Metastatic Uveal Melanoma and Clinical Results of a Phase I Study of the Protein Kinase C Inhibitor AEB071

Supplementary Table 1 shows the adverse events suspected to be study drug-related. Supplementary Table 2 shows the sequencing data availability by treatment group. Supplementary Table 3 shows the observed correlations between selected mutations/alterations. Supplementary Figure 1 shows the time on study for each patient. Supplementary Figure 2 shows the gene alterations ordered by chromosome and PFS. Supplementary Figure 3 shows gene alterations ordered by chromosome and percentage change from baseline. Supplementary Figure 4 shows Kaplan-Meier plot of PFS for patients with or without a GNAQ mutation.