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Dilated cardiomyopathy in a pediatric population: etiology and outcome predictors - a single-center experience
- Source :
- Future cardiology. 15(2)
- Publication Year :
- 2019
-
Abstract
- Aim: The aim of the study was to assess predictors of outcome in patients hospitalized for dilated cardiomyopathy (DCM) and severe left ventricular dysfunction. Patients & methods: 83 pediatric patients hospitalized for heart failure due to DCM with coexistent left ventricular dysfunction were enrolled.Results: Overall, 5-year survival free from heart transplantation was 69.8%. Normalization of left ventricular function was achieved in 39.8% of patients during follow-up: younger age, less necessity of inotropic support and other than idiopathic DCM predicted left ventricular function, while familial history for cardiac disease or sudden death and inotropic support during hospitalization were associated with poorer outcome. Conclusion: Almost 40% of patients with DCM experienced a complete normalization of cardiac function. Outcome was extremely variable according to the type of DCM.
- Subjects :
- Male
medicine.medical_treatment
Biostatistic
heart failure
pediatric cardiomyopathy
030204 cardiovascular system & hematology
heart transplantation
Muscular Dystrophies
Ventricular Function, Left
Electrocardiography
0302 clinical medicine
Risk Factors
Prevalence
030212 general & internal medicine
Prospective Studies
Registries
Muscular Dystrophie
left ventricular dysfunction
Heart transplantation
Ventricular Remodeling
left ventricular function normalization
Dilated cardiomyopathy
idiopathic cardiomyopathy
Left ventricular noncompaction cardiomyopathy
Prognosis
Survival Rate
Italy
Child, Preschool
cardiovascular system
Cardiology
Molecular Medicine
Female
Cardiology and Cardiovascular Medicine
Human
Cardiac function curve
Cardiomyopathy, Dilated
Heart Defects, Congenital
medicine.medical_specialty
Myocarditis
Prognosi
Biostatistics
Sudden death
Risk Assessment
Follow-Up Studie
03 medical and health sciences
Internal medicine
medicine
Humans
cardiovascular diseases
Idiopathic Cardiomyopathy
business.industry
anthracycline-related cardiomyopathy
Risk Factor
Stroke Volume
medicine.disease
dilated cardiomyopathy
Prospective Studie
myocarditi
Heart failure
left ventricular noncompaction cardiomyopathy
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 17448298
- Volume :
- 15
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Future cardiology
- Accession number :
- edsair.doi.dedup.....094e23b54d7e5c421f39667080349440