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Supplementary Tables from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers
- Publication Year :
- 2023
- Publisher :
- American Association for Cancer Research (AACR), 2023.
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Abstract
- Supplementary Tables S1-S12: Supplementary Table S1: Primer sequences used in this study. Supplementary Table S2: Clinical information of tumours analysed in the present study. Supplementary Table S3: Patients' characteristics. Supplementary Table S4: Likely causal mutations in mismatch repair genes detected in this study. Supplementary Table S5: List of Tier 2 mutations. Supplementary Table S6: Significantly mutated genes identified with MutSigCV. Supplementary Table S7: Genes differentially altered between Lynch syndrome-associated/Lynch-like tumours and MLH1 promoter-methylated tumours. Supplementary Table S8: Recurrent copy number alterations detected with allele-specific copy number analysis. Supplementary Table S9: Pathways detected from top 209 Tier 2 genes with The Database for Annotation, Visualization and Integrated Discovery. Supplementary Table S10: Pathways detected from significantly mutated genes with The Database for Annotation, Visualization and Integrated Discovery. Supplementary Table S11: Detected oncogenic alterations and associated mutations with uncertain significance. Supplementary Table S12: Complementary DNA sequences of fusion points confirmed by reverse-transcription polymerase chain reaction followed by Sanger sequencing.
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....09ee4d3885121e32029c75a83ced960a
- Full Text :
- https://doi.org/10.1158/1078-0432.22473842