The 9p21 coronary artery disease locus and kidney dysfunction in patients with Type 2 diabetes mellitus

Authors :: Thomas H. Hauser
Ernest V. Gervino
Alessandro Doria
Diego Bailetti
Vincenzo Trischitta
Christine Mendonca
Laura Pucci
Olga Lamacchia
Sabrina Prudente
Salvatore De Cosmo
Giuseppe Penno
Luana Mercuri
Hetal Shah
Mauro Cignarelli
Daniela Lucchesi
Publication Year :: 2012
Publisher :: OXFORD UNIV PRESS, 2012.
Abstract: Background. We investigated whether the coronary artery disease (CAD) locus on chromosome 9p21 (as represented by single nucleotide polymorphism rs2383206) is associated with low estimated glomerular filtration rate (eGFR) or increased urinary albumin excretion in patients with Type 2 diabetes mellitus (T2DM). Methods. Four samples, including a total of 3167 patients, were studied. The presence of low eGFR (

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