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Elimination and irrigation therapy to optimize the state of the nasal microbiome in children
- Source :
- Медицинский совет, Vol 0, Iss 1, Pp 50-58 (2021)
- Publication Year :
- 2021
- Publisher :
- Remedium, Ltd., 2021.
-
Abstract
- The article summarizes the results of the work of domestic and foreign researchers on the study of homeostasis of the nasal cavity, including the state of the microbiota of the nasal mucosa in healthy children and in inflammatory diseases of the upper respiratory tract. The normal microbiota of the nasal cavity is represented by corynebacteria (diphtheroids), neisseria, coagulasenegative staphylococci, alpha-hemolytic streptococci. From among the transient species, such species as Staphylococcus aureus, Escherihia coli, beta-hemolytic streptococci would be found in the specified biotope. The main attention is paid to the features of the nasal microbiota in newborns and young children (dependence of the nasal microbiota on the type of feeding, age and season). The role of hypercolonization by opportunistic microflora and its persistent potential (ability to biofilm formation, degradation of lysozyme, interferon) in the pathogenesis of inflammatory diseases of the upper respiratory tract is noted. The pathogenetic mechanisms providing multilevel protection of the organism from pathogens are considered. The expediency of using elimination-irrigation therapy as a hygienic means of sanitizing the nasal cavity in young children has been determined. The questions about the advantages of the use of isotonic solutions, their effectiveness for ensuring normal colonization resistance of the nasal mucosa are discussed. In conclusion, we must say that for hygienic care and sanitation purposes it is recommended only to rinse the nasal mucosa in newborns and infants using drops of isotonic saline solution and an aspirator to avoid aspiration and inflow of liquid into the cavity of Eustachian tube and middle ear, and also for the preventive purposes, as it allows to maintain homeostasis of the nasal mucosa and prevent the development of acute respiratory diseases.
- Subjects :
- 0301 basic medicine
Nasal cavity
Eustachian tube
030106 microbiology
nasal microbiota
Mucous membrane of nose
Colonisation resistance
medicine.disease_cause
elimination-irrigation therapy
03 medical and health sciences
homeostasis
otorhinolaryngologic diseases
medicine
Respiratory system
isotonic saline solutions
young children
business.industry
General Medicine
nasal cavity
030104 developmental biology
medicine.anatomical_structure
Staphylococcus aureus
Immunology
Middle ear
Medicine
business
Respiratory tract
Subjects
Details
- ISSN :
- 26585790 and 2079701X
- Database :
- OpenAIRE
- Journal :
- Meditsinskiy sovet = Medical Council
- Accession number :
- edsair.doi.dedup.....0a6fcfc1b6ce3d5b23dc14d6d1c3c765