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Retention of calcium from various xylitol-calcium combinations in rats
- Source :
- Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 205(3)
- Publication Year :
- 1994
-
Abstract
- Previous studies have shown that xylitol, the five-carbon sugar alcohol, increases the intestinal absorption of Ca in the rat. In this study an optimum xylitol:Ca molar ratio for Ca absorption and retention was determined in 10-week-old Long-Evans male rats. Xylitol was intubated with 20 mg of 45Ca (as 45CaCl2 or 45CaCO3) into the stomach of fasted rats in 1 ml water using xylitol:Ca molar ratios of 0:1, 0.5:1, 1:1, 1.5:1 or 2:1. Radioactivity of urine, feces and humerus was determined from 48-hr samples. The highest retention rate of 45Ca in the whole body or in the humerus was found when 114 mg of xylitol was given with Ca (xylitol:Ca molar ratio 1.5). Xylitol affected humeral retention more significantly than whole body retention. For comparison, the retention of 45Ca was determined from four lactose:CaCl2 combinations and from Ca-lactate and Ca-citrate salts. None of these combinations increased Ca retention significantly, although lactose at 114 mg dose showed slight positive effect. The results favor the use of a xylitol:Ca molar ratio of 1.5 in Ca supplements.
- Subjects :
- Molar
Male
chemistry.chemical_element
Urine
Calcium
Xylitol
General Biochemistry, Genetics and Molecular Biology
Intestinal absorption
Osmolar Concentration
Calcium Carbonate
chemistry.chemical_compound
Calcium Chloride
Feces
Animals
Food science
Lactose
Sugar alcohol
Intestinal Mucosa
chemistry.chemical_classification
Calcium Radioisotopes
food and beverages
Rats, Inbred Strains
Humerus
Rats
carbohydrates (lipids)
chemistry
Biochemistry
Intestinal Absorption
Subjects
Details
- ISSN :
- 00379727
- Volume :
- 205
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
- Accession number :
- edsair.doi.dedup.....0a8d2f029555266b15a77857dc8512f5