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Renal resistive index is associated with acute kidney injury in COVID-19 patients treated in the intensive care unit
- Source :
- The Ultrasound Journal, Vol 13, Iss 1, Pp 1-9 (2021), The Ultrasound Journal
- Publication Year :
- 2021
- Publisher :
- SpringerOpen, 2021.
-
Abstract
- Background Renal resistive index (RRI) is a promising tool for the assessment of acute kidney injury (AKI) in critically ill patients in general, but its role and association to AKI among patients with Coronavirus disease 2019 (COVID-19) is not known. Objective The aim of this study was to describe the pattern of RRI in relation to AKI in patients with COVID-19 treated in the intensive care unit. Methods In this observational cohort study, RRI was measured in COVID-19 patients in six intensive care units at two sites of a Swedish University Hospital. AKI was defined by the creatinine criteria in the Kidney Disease Improving Global Outcomes classification. We investigated the association between RRI and AKI diagnosis, different AKI stages and urine output. Results RRI was measured in 51 patients, of which 23 patients (45%) had AKI at the time of measurement. Median RRI in patients with AKI was 0.80 (IQR 0.71–0.85) compared to 0.72 (IQR 0.67–0.78) in patients without AKI (p = 0.004). Compared to patients without AKI, RRI was higher in patients with AKI stage 3 (median 0.83, IQR 0.71–0.85, p = 0.006) but not in patients with AKI stage 1 (median 0.76, IQR 0.71–0.83, p = 0.347) or AKI stage 2 (median 0.79, min/max 0.79/0.80, n = 2, p = 0.134). RRI was higher in patients with an ongoing AKI episode compared to patients who never developed AKI (median 0.72, IQR 0.69–0.78, p = 0.015) or patients who developed AKI but had recovered at the time of measurement (median 0.68, IQR 0.67–0.81, p = 0.021). Oliguric patients had higher RRI (median 0.84, IQR 0.83–0.85) compared to non-oliguric patients (median 0.74, IQR 0.69–0.81) (p = 0.009). After multivariable adjustment, RRI was independently associated with AKI (OR for 0.01 increments of RRI 1.22, 95% CI 1.07–1.41). Conclusions Critically ill COVID-19 patients with AKI have higher RRI compared to those without AKI, and elevated RRI may have a role in identifying severe and oliguric AKI at the bedside in these patients.
- Subjects :
- lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty
Point-of-care ultrasound
lcsh:R895-920
030204 cardiovascular system & hematology
urologic and male genital diseases
law.invention
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
law
Internal medicine
Intensive care
medicine
Radiology, Nuclear Medicine and imaging
Stage (cooking)
Ultrasonography
Creatinine
Radiological and Ultrasound Technology
medicine.diagnostic_test
business.industry
urogenital system
Acute kidney injury
Renal resistive index
COVID-19
030208 emergency & critical care medicine
Interventional radiology
medicine.disease
Intensive care unit
female genital diseases and pregnancy complications
Renal Doppler
chemistry
Original Article
business
human activities
Kidney disease
Cohort study
Subjects
Details
- Language :
- English
- ISSN :
- 25248987
- Volume :
- 13
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- The Ultrasound Journal
- Accession number :
- edsair.doi.dedup.....0ae57fbcfcbc776fce4c2e336390945a