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Rosa centifolia petal extract induces endothelium-dependent and endothelium-independent vasorelaxation in rat aorta and prevents accumulation of inflammatory factors in human umbilical vein endothelial cells
- Source :
- Journal of food biochemistryREFERENCES. 46(7)
- Publication Year :
- 2022
-
Abstract
- This study aims to investigate the vasorelaxation effects of a Rosa centifolia petal extract (ROSE CRYSTA®-70: ROSE-70) on the isolated aorta and the protective effect of ROSE-70 on human umbilical vein endothelial cells (HUVECs) dysfunction. ROSE-70 inhibited phenylephrine (PE) -induced contraction in an endothelium-dependent and endothelium-independent manner; however, this relaxation was lower in the endothelium-denuded aorta. ROSE-70-induced relaxation was attenuated by L-N
Details
- ISSN :
- 17454514
- Volume :
- 46
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of food biochemistryREFERENCES
- Accession number :
- edsair.doi.dedup.....0af33b540766d122208bcf29787e5028