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Management of an Immunocompromised Pediatric Patient With Multiple Hospitalizations for Symptomatic COVID-19

Management of an Immunocompromised Pediatric Patient With Multiple Hospitalizations for Symptomatic COVID-19

Authors :
Mackenzie N. DeVine
Juri Boguniewicz
Christine E. MacBrayne
Sarah Maxwell
Andrew S Haynes
Source :
Journal of Pediatric Hematology/Oncology
Publication Year :
2020
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2020.

Abstract

Relapse of infection due to SARS-CoV-2 has been rarely described and there is little guidance regarding the management of such cases in immunocompromised hosts. We present a case of an adolescent female with B-cell acute lymphoblastic leukemia hospitalized multiple times for symptomatic SARS-CoV-2 infection who was safely treated with 2 courses of remdesivir (RDV) and has had no additional readmissions to date. Though additional studies are needed to confirm the safety and efficacy of an additional course of RDV in the setting of relapsed or prolonged severe COVID-19, our observations suggest that a second course of RDV may be considered.

Details

Language :
English
ISSN :
10774114
Database :
OpenAIRE
Journal :
Journal of Pediatric Hematology/Oncology
Accession number :
edsair.doi.dedup.....0afeb0a0e00826d4a1a5aa3eef2be1a9
Full Text :
https://doi.org/10.1097/mph.0000000000002014