Back to Search
Start Over
DNAzyme-Assisted Nano-Herb Delivery System for Multiple Tumor Immune Activation
DNAzyme-Assisted Nano-Herb Delivery System for Multiple Tumor Immune Activation
- Source :
- Small (Weinheim an der Bergstrasse, Germany). 18(45)
- Publication Year :
- 2022
-
Abstract
- As a promising therapeutic strategy against cancer, immunotherapy faces critical challenges, especially in solid tumors. Immune checkpoint blockade therapy, particularly blocking the interaction of the programmed cell death 1 (PD1)-PD1 ligand 1 (PD-L1) axis, can reverse the suppression of T cells so as to destroy tumor cells and exert antitumor effects. Here, a strategy of multiple activation of immune pathways is developed, to provide supporting evidence for potential antitumor therapies. Briefly, a pH/glutathione responsive drug-loading hollow-manganese dioxide (H-MnO
Details
- ISSN :
- 16136829
- Volume :
- 18
- Issue :
- 45
- Database :
- OpenAIRE
- Journal :
- Small (Weinheim an der Bergstrasse, Germany)
- Accession number :
- edsair.doi.dedup.....0b94feb0df295a3184b903d53d81e850