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Comparison of two techniques (intermittent intravenous bolus morphine vs. morphine infusion) for analgesic titration in patients who had advanced cancer with severe pain: a prospective randomised study
- Source :
- BMJ supportivepalliative care.
- Publication Year :
- 2020
-
Abstract
- ObjectiveTo compare the analgesic efficacy of two techniques of morphine titration (intermittent intravenous bolus vs infusion) by calculating rescue dosage in a day at 1 week after analgesic titration.MethodsOne hundred and forty cancer patients were randomised into two groups. In group 1, intravenous morphine 1.5 mg bolus given every 10 min until Numerical Rating Scale (NRS) pain score ResultsThe rescue dosage in a day at 1-week post discharge from the palliative care unit was significantly higher in group 1 as compared with group 2.ConclusionIntravenous infusion morphine may be a better analgesic titration technique for analgesia in patients with advanced cancer.Trial registration numberCTRI/2018/04/013369.
- Subjects :
- Palliative care
Oncology (nursing)
business.industry
Analgesic
Medicine (miscellaneous)
Cancer
General Medicine
Intravenous bolus
medicine.disease
Advanced cancer
03 medical and health sciences
Medical–Surgical Nursing
0302 clinical medicine
030220 oncology & carcinogenesis
Anesthesia
Morphine
medicine
In patient
030212 general & internal medicine
Bolus (digestion)
business
medicine.drug
Subjects
Details
- ISSN :
- 20454368
- Database :
- OpenAIRE
- Journal :
- BMJ supportivepalliative care
- Accession number :
- edsair.doi.dedup.....0bd29cab2378887897c5aba1063f4462