Additional file 1 of Sex hormones influence survival of patients with metastatic urothelial carcinoma undergoing immune checkpoint therapy

Additional file 1. Changes in blood levels of luteinizing hormone, follicle-stimulating hormone, LH to FSH ratio, prolactin, estrogen and testosterone prior to the therapy start, after 6/8 weeks and 12/14 weeks after the therapy begin in females and males. Statistical significance was assessed by Friedman test with Kendall’s W effect size statistic. Points represent single observations. Gray lines connect observations belonging to the same participant. Numbers of complete observations are displayed in the plot captions. Effect size and p values are presented in the plot facets. Female, male.