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Polyketides from mantis-associated fungus Daldinia eschscholzii IFB-TL01
- Source :
- Chemistrybiodiversity. 12(9)
- Publication Year :
- 2014
-
Abstract
- Three new polyketides, named daldinone F (1), nodulisporin G (2), and dalmanol C (3), together with five known compounds, 4-8, were isolated from cultures of Daldinia eschscholzii. The structures of the new compounds were elucidated by extensive NMR and MS analyses. Compound 1 showed moderate cytotoxic activity against SW480 cancer cells with an IC50 value of 9.59 μM, and its absolute configuration was determined by single crystal X-ray diffraction.
- Subjects :
- Models, Molecular
Magnetic Resonance Spectroscopy
biology
Xylariales
Stereochemistry
Chemistry
Daldinia eschscholzii
Absolute configuration
Bioengineering
General Chemistry
General Medicine
Nuclear magnetic resonance spectroscopy
Fungus
biology.organism_classification
Crystallography, X-Ray
Biochemistry
Polyketides
Molecular Medicine
Molecular Biology
Subjects
Details
- ISSN :
- 16121880
- Volume :
- 12
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Chemistrybiodiversity
- Accession number :
- edsair.doi.dedup.....0c16c786e87fbe41c7f59ef3c16c50c0