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bcbioRNASeq: R package for bcbio RNA-seq analysis

Authors :
John N. Hutchinson
Oliver Hofmann
Radhika S. Khetani
Meeta Mistry
Victor Barrera
Kayleigh Rutherford
Lorena Pantano
Shannan J. Ho Sui
Brad Chapman
Michael J. Steinbaugh
Rory Kirchner
Mary E. Piper
Source :
F1000Research. 6:1976
Publication Year :
2018
Publisher :
F1000 Research Ltd, 2018.

Abstract

RNA-seq analysis involves multiple steps, from processing raw sequencing data to identifying, organizing, annotating, and reporting differentially expressed genes. bcbio is an open source, community-maintained framework providing automated and scalable RNA-seq methods for identifying gene abundance counts. We have developed bcbioRNASeq, a Bioconductor package that provides ready-to-render templates, objects and wrapper functions to post-process bcbio RNA sequencing output data. bcbioRNASeq helps automate the generation of high-level RNA-seq reports, facilitating the quality control analyses, identification of differentially expressed genes and functional enrichment analyses.

Details

ISSN :
20461402
Volume :
6
Database :
OpenAIRE
Journal :
F1000Research
Accession number :
edsair.doi.dedup.....0c329edf415678f498a4aa657bcba303
Full Text :
https://doi.org/10.12688/f1000research.12093.2