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Clinical Features and Survival Outcomes in Patients with Multiple Myeloma: Analysis of Web-Based Data from the Korean Myeloma Registry

Authors :
Yeung-Chul Mun
Jung Hye Kwon
Hye Jin Kang
Bong Seog Kim
Yang Soo Kim
Hawk Kim
Hwi Joong Yoon
Hyeon Seok Eom
Jung Lim Lee
Hyeok Shim
Chul Soo Kim
Chong Won Park
Joon Seong Park
Byung Soo Kim
Ho Young Kim
Jong Youl Jin
Jae Yong Kwak
Jae Hoon Lee
Deog Yeon Jo
Jin Seok Kim
Chang-Ki Min
Seok Jin Kim
Hyunchoon Shin
Sung-Soo Yoon
Sang Kyun Sohn
Hyo Jung Kim
Je-Jung Lee
Dong Soon Lee
Ho Jin Shin
Jong Ho Won
Young Rok Do
Young Don Joo
Gyeong Won Lee
Min Kyoung Kim
Cheolwon Suh
Ki-Hyun Kim
Hun Mo Ryoo
Sung-Hyun Kim
Sukjoong Oh
Soo Mee Bang
Seong Kyu Park
Source :
Acta Haematologica. 122:200-210
Publication Year :
2009
Publisher :
S. Karger AG, 2009.

Abstract

Aim: The Korean Multiple Myeloma Working Party performed a nationwide registration of multiple myeloma patients via a web-based data bank system. Methods: We retrospectively analyzed registered data from 3,209 patients since 1999. Results: The median overall survival (OS) was 50.13 months (95% confidence interval: 46.20–54.06 months). Patients ≤40 years demonstrated a longer OS than patients >65 years of age (median OS 71.13 vs. 36.73 months, p < 0.001). Patients who received novel agents at any time during their treatments showed a longer OS than patients who did not (median OS 42.23 vs. 55.50 months, p < 0.001). Response to treatment was associated with OS, with tandem autologous stem cell transplantation (SCT) producing longer OS than single autologous SCT. Conclusions: We demonstrated associations between survival outcomes and treatment modalities as well as baseline disease characteristics in a registry of multiple myeloma patients using a web-based data analysis.

Details

ISSN :
14219662 and 00015792
Volume :
122
Database :
OpenAIRE
Journal :
Acta Haematologica
Accession number :
edsair.doi.dedup.....0c747287c957bf49f7a42c6a4b150ba3