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The Risk for Glucose Intolerance after Gestational Diabetes Mellitus since the Introduction of the IADPSG Criteria: A Systematic Review and Meta-Analysis
- Source :
- Journal of Clinical Medicine, Vol 8, Iss 9, p 1431 (2019), Journal of Clinical Medicine
- Publication Year :
- 2019
- Publisher :
- MDPI AG, 2019.
-
Abstract
- The aim of the study was to assess the postpartum risk for glucose intolerance since the introduction of the 'International Association of Diabetes and Pregnancy Study Groups' (IADPSG) criteria for gestational diabetes mellitus (GDM). Studies published since 2010 were included, which evaluated the risk for type 2 diabetes mellitus (T2DM), impaired glucose tolerance (IGT), and cardiovascular (CV) events in women with previous GDM compared to normal glucose tolerant women. We included forty-three studies, evaluating 4,923,571 pregnant women of which 5.8% (284,312) had a history of GDM. Five studies used IADPSG criteria (n = 6174 women, 1314 with GDM). The overall pooled relative risk (RR) for postpartum T2DM was 7.42 (95% CI: 5.99-9.19) and the RR for postpartum T2DM with IADPSG criteria was 6.45 (95% CI: 4.74-8.77) compared to the RR of 9.08 (95% CI: 6.96-11.85; p = 0.17) for postpartum T2DM based on other diagnostic criteria. The RR for postpartum IGT was 2.45 (95% CI: 1.92-3.13), independent of the criteria used. None of the available studies with IADPSG criteria evaluated the risk for CV events. Women with a history of GDM based on the IADPSG criteria have a similarly increased risk for postpartum glucose intolerance compared to GDM based on other diagnostic criteria. More studies with GDM based on the IADPSG criteria are needed to increase the quality of evidence concerning the long-term metabolic risk. ispartof: JOURNAL OF CLINICAL MEDICINE vol:8 issue:9 ispartof: location:Switzerland status: published
- Subjects :
- medicine.medical_specialty
endocrine system diseases
lcsh:Medicine
030209 endocrinology & metabolism
Type 2 diabetes
Review
Impaired glucose tolerance
03 medical and health sciences
0302 clinical medicine
Diabetes mellitus
Medicine
030212 general & internal medicine
postpartum
Pregnancy
business.industry
Obstetrics
lcsh:R
Type 2 Diabetes Mellitus
nutritional and metabolic diseases
General Medicine
medicine.disease
stroke
gestational diabetes mellitus
Gestational diabetes
impaired glucose tolerance
myocardial infarction
glucose intolerance
International Association of Diabetes and Pregnancy Study Groups (IADPSG)
Meta-analysis
Relative risk
diagnostic criteria
type 2 diabetes
business
Subjects
Details
- Language :
- English
- ISSN :
- 20770383
- Volume :
- 8
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Medicine
- Accession number :
- edsair.doi.dedup.....0c950b4d23b26311bf3ee3aea9b37323