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An integrative functional genomics approach reveals EGLN1 as a novel therapeutic target in KRAS mutated lung adenocarcinoma
- Source :
- Molecular Cancer, Molecular Cancer, Vol 20, Iss 1, Pp 1-6 (2021)
- Publication Year :
- 2021
- Publisher :
- BioMed Central, 2021.
-
Abstract
- No Abstract available.
- Subjects :
- Cancer Research
Adenocarcinoma of Lung
Antineoplastic Agents
medicine.disease_cause
lcsh:RC254-282
Models, Biological
CRISPR/Cas9 screening
Hypoxia-Inducible Factor-Proline Dioxygenases
Proto-Oncogene Proteins p21(ras)
Gene Knockout Techniques
medicine
Biomarkers, Tumor
KRAS
Humans
Molecular Targeted Therapy
Lung cancer
Letter to the Editor
Lung
biology
Disease Management
Genomics
HIF1A
medicine.disease
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Hypoxia-Inducible Factor 1, alpha Subunit
medicine.anatomical_structure
Oncology
Mutation
biology.protein
Cancer research
Molecular Medicine
Adenocarcinoma
Disease Susceptibility
Functional genomics
EGLN1
Subjects
Details
- Language :
- English
- ISSN :
- 14764598
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Molecular Cancer
- Accession number :
- edsair.doi.dedup.....0ca0396aa588cf6d309a7b200ff2a9a5