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Development of reproductive engineering techniques at the RIKEN BioResource Center
- Source :
- Experimental Animals
- Publication Year :
- 2017
- Publisher :
- Japanese Association for Laboratory Animal Science, 2017.
-
Abstract
- Reproductive engineering techniques are essential for assisted reproduction of animals and generation of genetically modified animals. They may also provide invaluable research models for understanding the mechanisms involved in the developmental and reproductive processes. At the RIKEN BioResource Center (BRC), I have sought to develop new reproductive engineering techniques, especially those related to cryopreservation, microinsemination (sperm injection), nuclear transfer, and generation of new stem cell lines and animals, hoping that they will support the present and future projects at BRC. I also want to combine our techniques with genetic and biochemical analyses to solve important biological questions. We expect that this strategy makes our research more unique and refined by providing deeper insights into the mechanisms that govern the reproductive and developmental systems in mammals. To make this strategy more effective, it is critical to work with experts in different scientific fields. I have enjoyed collaborations with about 100 world-recognized laboratories, and all our collaborations have been successful and fruitful. This review summarizes development of reproductive engineering techniques at BRC during these 15 years.
- Subjects :
- 0301 basic medicine
nuclear transfer
Nuclear Transfer Techniques
Engineering
Review
ICSI
General Biochemistry, Genetics and Molecular Biology
Sperm injection
Animals, Genetically Modified
03 medical and health sciences
Reproductive Techniques
Japan
Animals
mouse
Insemination, Artificial
Cryopreservation
General Veterinary
business.industry
General Medicine
Data science
stem cell
030104 developmental biology
Animal Science and Zoology
Stem cell line
Genetic Engineering
business
Stem Cell Transplantation
Subjects
Details
- ISSN :
- 18817122 and 13411357
- Volume :
- 66
- Database :
- OpenAIRE
- Journal :
- Experimental Animals
- Accession number :
- edsair.doi.dedup.....0d25bc15993f9235f8930063ace0a703