Back to Search Start Over

One-Stage Versus Sequential Hybrid Radiofrequency Ablation: An In Vitro Evaluation

Authors :
Jos G. Maessen
Mark La Meir
Kevin Vernooy
Carlo de Asmundis
Bart Maesen
Francesco Matteucci
Sandro Gelsomino
CTC
RS: Carim - V04 Surgical intervention
MUMC+: MA Med Staf Spec CTC (9)
RS: Carim - H08 Experimental atrial fibrillation
MUMC+: MA Med Staf Artsass CTC (9)
Cardiologie
MUMC+: MA Med Staf Spec Cardiologie (9)
RS: Carim - H01 Clinical atrial fibrillation
RS: Carim - H06 Electro mechanics
MUMC+: MA Cardiothoracale Chirurgie (3)
Clinical sciences
Heartrhythmmanagement
Surgical clinical sciences
Cardiac Surgery
Source :
Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 15(4), 338-345. SAGE Publications Inc.
Publication Year :
2020
Publisher :
SAGE Publications, 2020.

Abstract

Objective To compare lesion size and depth between a 1-step, a sequential, and a delayed radio-frequency ablation in a hybrid setup. Methods Left atrium tissues obtained from fresh porcine hearts were mounted into the ABLABOX simulator. Based on the time differences between the index epicardial (epi) and consequent endocardial (endo) ablation, 3 study groups were compared: a 1-stage (SEQ- 0) group (0-minute delay), an SEQ 1 group (60-minute delay), and an SEQ 2 group (240-minute delay). During the experiment, a constant epicardial (300 gr) and endocardial (30 gr) force were applied. Per group, 20 samples were studied, and the resulting lesion size and depth were quantified with morphometric evaluation. Results Overall, no transmural lesion was obtained. Lesions in SEQ 0 had better maximum and minimum diameters ( P < 0.001), a larger total area ( P < 0.001), and volume ( P < 0.001) than SEQ 1 and SEQ 2. There was no statistical difference in morphometric parameters (all, P > 0.05) between the delayed procedures (SEQ 1 and SEQ 2). Conclusions In our in vitro model, different time sequences of combined epi–endo ablation did not result in transmural lesions. However, simultaneous epi–endo ablation produced broader and deeper lesions. Our findings need to be confirmed by further research.

Details

ISSN :
15590879 and 15569845
Volume :
15
Database :
OpenAIRE
Journal :
Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Accession number :
edsair.doi.dedup.....0d51669c90ddd1248b695b10b1900c25