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A switchable dual organocatalytic system and the enantioselective total synthesis of the quadrane sesquiterpene suberosanone

Authors :
Jeremy Godemert
Michel Giorgi
Jean-Valère Naubron
Jean Rodriguez
Nicolas Vanthuyne
Marc Presset
Yajun Ren
Yoann Coquerel
Institut des Sciences Moléculaires de Marseille (ISM2)
Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Spectropôle - Aix Marseille Université (AMU SPEC)
Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC)
Source :
Chemical Communications, Chemical Communications, 2016, 52 (39), pp.6565-6568. ⟨10.1039/c6cc01689h⟩, Chemical Communications, Royal Society of Chemistry, 2016, 52 (39), pp.6565-6568. ⟨10.1039/c6cc01689h⟩
Publication Year :
2016
Publisher :
Royal Society of Chemistry (RSC), 2016.

Abstract

International audience; The combination of aminocatalysis with N-heterocyclic carbene catalysis has been extended to a switchable dual catalytic system, which allowed a direct enantioselective entry to bridged bicyclo[3.n.1] ring systems and the total synthesis of the natural product (1R)-suberosanone.

Details

ISSN :
1364548X and 13597345
Volume :
52
Database :
OpenAIRE
Journal :
Chemical Communications
Accession number :
edsair.doi.dedup.....0d69be01022b67f01b988de3e9839da0
Full Text :
https://doi.org/10.1039/c6cc01689h