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Acute myocardial infarction versus other cardiovascular events in community-acquired pneumonia
- Source :
- ERJ Open Research, Vol 1, Iss 1 (2015)
- Publication Year :
- 2015
- Publisher :
- European Respiratory Society, 2015.
-
Abstract
- The aim of the present study was to define the prevalence, characteristics, risk factors and impact on clinical outcomes of acute myocardial infarction (AMI) versus other cardiovascular events (CVEs) in patients with community-acquired pneumonia (CAP).This was an international, multicentre, observational, prospective study of CAP patients hospitalised in eight hospitals in Italy and Switzerland. Three groups were identified: those without CVEs, those with AMI and those with other CVEs.Among 905 patients, 21 (2.3%) patients experienced at least one AMI, while 107 (11.7%) patients experienced at least one other CVE. Patients with CAP and either AMI or other CVEs showed a higher severity of the disease than patients with CAP alone. Female sex, liver disease and the presence of severe sepsis were independent predictors for the occurrence of AMI, while female sex, age >65 years, neurological disease and the presence of pleural effusion predicted other CVEs. In-hospital mortality was significantly higher among those who experienced AMI in comparison to those experiencing other CVEs (43% versus 21%, p=0.039). The presence of AMI showed an adjusted odds ratio for in-hospital mortality of 3.57 (p=0.012) and for other CVEs of 2.63 (p=0.002).These findings on AMI versus other CVEs as complications of CAP may be important when planning interventional studies on cardioprotective medications.
- Subjects :
- Pulmonary and Respiratory Medicine
medicine.medical_specialty
business.industry
Pleural effusion
lcsh:R
lcsh:Medicine
Odds ratio
Disease
medicine.disease
3. Good health
03 medical and health sciences
Pneumonia
Liver disease
0302 clinical medicine
030228 respiratory system
Community-acquired pneumonia
Internal medicine
Medicine
030212 general & internal medicine
Myocardial infarction
cardiovascular diseases
business
Intensive care medicine
Prospective cohort study
health care economics and organizations
Subjects
Details
- Language :
- English
- ISSN :
- 23120541
- Volume :
- 1
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- ERJ Open Research
- Accession number :
- edsair.doi.dedup.....0d7bdcf7c79bd78cd5dba3248d7555c8