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Expressing the human genome
- Source :
- Nature. 409:832-833
- Publication Year :
- 2001
- Publisher :
- Springer Science and Business Media LLC, 2001.
-
Abstract
- We have searched the human genome for genes encoding new proteins that may be involved in three nuclear gene expression processes: transcription, pre-messenger RNA splicing and polyadenylation. A plethora of potential new factors are implicated by sequence in nuclear gene expression, revealing a substantial but selective increase in complexity compared with Drosophila melanogaster and Caenorhabditis elegans. Although the raw genomic information has limitations, its availability offers new experimental approaches for studying gene expression.
- Subjects :
- Transcriptional Activation
Genetics
Multidisciplinary
Nuclear gene
Transcription, Genetic
Genome, Human
RNA Splicing
Alternative splicing
Gene Expression
Biology
Genome
Transcription (biology)
Human Genome Project
RNA splicing
Gene expression
Animals
Humans
Human genome
in silico analysis
human genome
transcrition factors
splicing factors
Poly A
Gene
Transcription Factors
Subjects
Details
- ISSN :
- 14764687 and 00280836
- Volume :
- 409
- Database :
- OpenAIRE
- Journal :
- Nature
- Accession number :
- edsair.doi.dedup.....0d81a3ecc0056522e08d8fe1cbe541a7