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Low-Dose Radiation Advances in Coronary Computed Tomography Angiography in the Diagnosis of Coronary Artery Disease
- Source :
- Current Cardiology Reviews
- Publication Year :
- 2019
-
Abstract
- Background: Coronary computed tomography angiography (CCTA) is now widely used in the diagnosis of coronary artery disease since it is a rapid, minimally invasive test with a diagnostic accuracy comparable to coronary angiography. However, to meet demands for increasing spatial and temporal resolution, higher x-ray radiation doses are required to circumvent the resulting increase in image noise. Exposure to high doses of ionizing radiation with CT imaging is a major health concern due to the potential risk of radiation-associated malignancy. Given its increasing use, a number of dose saving algorithms have been implemented to CCTA to minimize radiation exposure to “as low as reasonably achievable (ALARA)” without compromising diagnostic image quality. Objective: The purpose of this review is to outline the most recent advances and current status of dose saving techniques in CCTA. Methods: PubMed, Medline, EMBASE and Scholar databases were searched to identify feasibility studies, clinical trials, and technology guidelines on the technical advances in CT scanner hardware and reconstruction software. Results: Sub-millisievert (mSv) radiation doses have been reported for CCTA due to a combination of strategies such as prospective electrocardiogram-gating, high-pitch helical acquisition, tube current modulation, tube voltage reduction, heart rate reduction, and the most recent novel adaptive iterative reconstruction algorithms. Conclusion: Advances in radiation dose reduction without loss of image quality justify the use of CCTA as a non-invasive alternative to coronary catheterization in the diagnosis of coronary artery disease.
- Subjects :
- Male
medicine.medical_specialty
iterative reconstruction
Image quality
Computed Tomography Angiography
Iterative reconstruction
Coronary Artery Disease
030204 cardiovascular system & hematology
Radiation Dosage
effective radiation dose
Article
030218 nuclear medicine & medical imaging
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Tube current modulation
Image noise
medicine
Humans
Coronary computed tomography angiography
image quality
prospective electrocardiogram-gating
Prospective Studies
business.industry
General Medicine
medicine.disease
tube voltage reduction
Clinical trial
tube current modulation
Female
Radiology
Cardiology and Cardiovascular Medicine
business
Low Dose Radiation
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Current Cardiology Reviews
- Accession number :
- edsair.doi.dedup.....0d968041e9b1a01891b9abaf91af35e3